Characteristics and ROC curve analysis of ankle injury in Kashin-Beck disease / 西安交通大学学报(医学版)

ABSTRACT

Objective:To investigate the characteristics of ankle talus by CT scanning in patients with Kashin-Beck disease. Methods: We included 40 patients with ankle pain for this study. CT examination was carried out to measure talus diameter, i.e., from the upper at inside to the lower at outside and from the upper at outside to the lower at inside in coronal direction; from the upper at front to the lower at behind, from upper at front to the upper at behind in sagittal direction. The statistically significant indexes were included in the ROC curve analysis. Results:CT measurement of the talus in ankle joints showed that the distance of the talus in ankle joints from the upper at outside to the lower at inside (3.76±0.34)cm, the upper at front to the lower at behind (4.98±0.36)cm in KBD group were significantly lower than those in OA group (4.26±0.34)cm and (5.40±0.37)cm, which was significantly difference (t=-3.599, 4.646, P=0.00). ROC curve analysis showed that there was significant difference between KBD group and OA group, and the cut-off value of the distance from the upper at outside to the lower at inside was 4.055cm, with sensitivity of 70% and specificity of 90%. When the cut-off value of the distance from the upper at front to the lower at behind was 5.41cm, the sensitivity was 65% and the specificity was 95%. Conclusion: The distance of the talus of KBD ankle joints from the upper at outside to the lower at inside (cut-off value of 4.055 cm) in coronal direction and the upper at front to the lower at behind (cut-off value was 5.41 cm) in sagittal direction can be used as specific diagnostic indicators of ankle joint damage for KBD in adults.