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Significance of carbohydrate antigen 50 expression in colorectal carcinoma / 西安交通大学学报·英文版
Academic Journal of Xi&#39 ; an Jiaotong University;(4): 249-251, 2009.
Article in Chinese | WPRIM | ID: wpr-844762
ABSTRACT

Objective:

To evaluate the significance of carbohydrate antigen 50 (CA50) expression in colorectal carcinoma.

Methods:

Immunohistochemical staining was used to detect CA50 expression in 10 cases of normal colorectal mucosa and 40 cases of cancer mucosa.

Results:

The expression of CA50 increased in normal colorectal mucosa, cancer distant mucosa, cancer adjacent mucosa and cancer mucosa, and there were significant differences among them (P < 0.05). The expression of CA50 in colorectal carcinoma was correlated with the degree of differentiation, Duke's stage and lymphatic metastases (P<0.05).

Conclusion:

The expression of CA50 can be used as a valuable index in evaluating the biological characteristics and prognosis of colorectal carcinoma.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Academic Journal of Xi&#39;an Jiaotong University Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Academic Journal of Xi&#39;an Jiaotong University Year: 2009 Type: Article