Plant-derived exosomes: research progress / 国际药学研究杂志

ABSTRACT

Exosomes are nanoscale vesicles secreted by plant cells, containing DNA, small RNA(sRNA), microRNA(miRNA), protein and other substances and mediating cell-cell communication. miRNA is a highly efficient gene expression regulator, which can regulate cross-border gene expression. sRNA transfers between host and organism through plasma-desmata and induces gene silencing. Plant exosomes exert anti-inflammatory, anti-virus, anti-fibrosis, anti-tumor and other related effects, via the substances contained, and participate in the defense response of pathogen invasion. Most plant exosomes are edible and can be used as carriers to deliver specific drugs, with no toxicity and side effects. Plant exosomes have become a hotspot of researches. This paper summarizes and analyzes the progress in the plant exosomes research reported in the literature in recent years, focusing on the source and function of medicinal plant exosomes, so as to provide reference for future studies on plant exosomes.