Research progress in pharmacological effects and quantitative methods for biles acids in Calculus Bovis / 国际药学研究杂志

ABSTRACT

Nature Calculus Bovis is one of the precious traditional Chinese medicines, which is the dried gallstone in gallbladder, bile duct or hepatic duct. In order to meet the clinical needs, we have developed artificial Calculus Bovis, invitro and other varieties. Calculus Bovis mainly contains bile pigments, bile acids, amino acids, inorganic elements and other types of components. Besides bile pigments, bile acids is the second largest of the active ingredients of Calculus Bovis, which is closely related to the antipyretic and analgesic, antiinflammatory effect and depressurization. The article outlines and summarizes the study progress in pharmacological effects and quantitative methods for components of bile acids in Calculus Bovis and its substitutes and preparations, aiming to provide a reference for subsequent research as well as quality control.