Thrombopoietin and acute radiation sickness / 国际药学研究杂志

ABSTRACT

Megakaryocytic hematopoietic disorders is one of the leading causes of death in patients with acute radiation sickness bleeding. Thrombopoietin (TP0)the main stimulation factor of megakaryocytopoiesis ’ can promote megakaryocytic hematopoietic recovery after radiation injury and increase peripheral platelet count. Early application of TP0 after irradiation can play a key role in prevention and treatment of bleeding complications of acute radiation sickness. Studies have shown that TP0 may have a stronger role in promoting hematopoiesis. In this paper,a brief overview of new progress on the TP0 and acute radiation sickness is summarized.