Role of tailless like protein, an orphan nuclear receptor n neural stem cell proliferation / 国际药学研究杂志

ABSTRACT

Orphan nuclear receptor Tailless like protein(TLX) is a transcription factor like a nucleoprotein. The newest research has found that TLX had an mportant influence on maintenance of cell functions, and played a critical role n neural stem cell proliferation. This review discusses the roles that the orphan nuclear receptor TLX plays on the process of neural stem cell proliferation and analyzes the molecular mechanisms of TLX. This review may also provide a new potential drug target for the treatment of neurode-generative diseases.