A new approach for exploiting microbial new strain resources for drug screening / 国际药学研究杂志
Journal of International Pharmaceutical Research
;
(6): 1-7, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-845964
ABSTRACT
Generally absolute majority of wild-type microbial strains do not produce bioactive metabolites, resulting in large numbers of so-called 'useless strains' stocked or destroyed. These strains, however, would become a great source of bioactive meabolites if their secondary metabolism could be altered to produce diverse metabolites. We have therefore undertaken a research work on exploiting microbial new strain resources for drug screening by altering secondary metabolism of the 'useless strains' to discover bioactive metabolites. A considerable progress with expectant advantage desired has been made in the studies on marine-derived actinomycetic and fungal strains. This paper summarizes our research results including several new developments in brief.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Screening study
Language:
Chinese
Journal:
Journal of International Pharmaceutical Research
Year:
2010
Type:
Article
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