A new benzofuran from Penicillium oxalicum, an endophytic fungus isolated from Pseudostellariaheterophylla / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 5681-5686, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-846037
ABSTRACT
Objective:
To study the secondary metabolites of Penicillium oxalicum, an endophytic fungus isolated from the medicinal plant Pseudostellariaheterophylla.Methods:
The secondary metabolites were isolated by silica gel, Sephadex LH-20 column chromatographies, and prep-TLC methods. Their structures were elucidated by using various spectroscopic techniques including HRESIMS and NMR spectra.Results:
A benzofuran compound 5,7-dihydroxy-2-methylbenzofuran-3-carboxylic acid (1), five isocoumarins including (3R,4R)-(-)-4-hydroxymellein (2), O-methylmellein (3), acremonone G (4), decarboxycitrinone (5) and decarboxyhydroxycitrinone (6), four bisabolane-type sesquiterpenoids including (7S,11S)-(+)-12-acetoxysydonic acid (7), (S)-(+)-11-dehydrosydonic acid (8), sydonic acid (9) and 1-hydroxy-boivinianin A (10), as well as two meroterpenoid-type alkaloids decaturin D (11) and decaturinC (12) were isolated.Conclusion:
Compound 1 is a new benzofuran compound and named as oxafuranone A, while compounds 2-6 and 10 are characterized from P. oxalicum for the first time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2020
Type:
Article
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