Application of lipidomics on research of traditional Chinese medicine / 中草药

ABSTRACT

Lipidomics is a newly emerged discipline that systematically studies the types, functions and metabolic pathways of lipids in organisms, which can identify biomarkers and molecular mechanisms of diseases or drugs by analyzing changes in lipid metabolism networks from different physiological or pathological states. As an important component of systems biology, lipidomics has the research mentality which is similar to the overall concept as well as the system theory of traditional Chinese medicine (TCM). Therefore, lipidomics becomes a powerful tool to promote the modernization of TCM. Lipidomics technology is briefly described in this paper, and the application of lipidomics technology on research of TCM including pharmacodynamics, action mechanism and toxicity are summed up, and at the same time the experience of other disciplines in the research of Chinese materia medica property theory and quality control of TCM are combined to expand the application ideas of lipidomics in TCM research, as well as provide references for the organic integration between TCM theory and modern technology.