Research progress on synthesis of intermediates in derivatization of β-elemene / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 4547-4558, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-846215
ABSTRACT
β-Elemene is the main active ingredient of elemene, a broad-spectrum anti-cancer botanical drug, which is also the main isomer of elemene's four isomers. The synthesis of some key intermediates were generalized and summarized during the derivatization of β-elemene, wherein the preparation methods, reaction conditions, yields, characterization data of these intermediates were listed. The purpose of this paper is to facilitate people in understanding and grasping the most optimal synthesis of these intermediates up to date, to inspire people pursuing further synthesis improvement, and to stimulate generation of new ideas for future derivatization of β-elemene.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2020
Type:
Article
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