Research progress of quality marker during Chinese materia medica processing / 中草药

ABSTRACT

As a traditional pharmacy technology, Chinese materia medica processing is the key link between traditional Chinese medicine and Chinese pharmacy. Some complex chemical changes occur in the processed Chinese medicinal materials, and the chemical changes in these materials are the significant causes leading to the changes in the nature and flavor of medicines before and after processing. A key restraint factor of the modernization of Chinese materia medica is the quality control of Chinese materia medica, which has always been a research focus in sociology and traditional Chinese medicine field. A new concept of "Q-marker" was first put forward by academician Chang-xiao Liu in 2016, which prompted a heated discussion in the Chinese medicine community field. Combining the research thinking "Q-marker" with Chinese materia medica processing, clarifying chemical composition changes during Chinese materia medica processing, and forming a new idea of quality control with the characteristic of Chinese materia medica processing are beneficial to accelerate the development and perfection of quality control methods for Chinese materia medica processing.