Chemical constituents from roots of Arctium lappa / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 912-917, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-846589
ABSTRACT
Objective:
To research the chemical constituents from the roots of Arctium lappa.Methods:
The compounds were isolated and purified by column chromatography over normal phase silical gel, reverse phase silical gel, ODS column chromatography and semi-preparative HPLC. Their structures were identified by various spectroscopic analysis, including NMR.Results:
Fourteen compounds were isolated from the 55% EtOH extract of the roots of A. lappa. And their structure were identified as 1,5-di-O-caffeoyl-3-O-maloyl quinic acid (1), 3,5-di-O-caffeoyl-1-O-(2-O-caffeoyl-4-maloyl)-quinic acid (2), 3,5-di-O- caffeoyl-1-(2-O-caffeoyl-4-maloyl methyl ester)-quinic acid (3), 3,5-di-O-caffeoyl-1-O-succinyl methyl ester quinic acid (4), 3,4-di-O-caffeoyl-1-O-succinyl methyl ester quinic acid (5), 1,3,5-tri-O-caffeoyl-4-O-succinyl quinic acid (6), 1,5-di-O- caffeoyl-3-O-succinyl quinic acid (7), 1,5-di-O-caffeoyl-4-O-succinyl quinic acid (8), 1,5-di-O-caffeoyl-4-O-succinyl methyl ester quinic acid (9), 1,5-di-O-caffeoyl-3-O-succinyl methyl ester quinic acid (10), 1,3,4-tri-O-caffeoyl quinic acid (11), 1,4,5-tri-O-caffeoyl quinic acid methyl ester (12), 3-O-caffeoyl quinic acid (13), and 4-hydroxy-phenylacetic acid (14).Conclusion:
Compounds 3-5, 9, 11, 12 are obtained from Arctium genus for the first time, and compound 14 is isolated from A. lappa for the first time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2020
Type:
Article
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