A Case of Polymorphic Pemphigoid / 대한피부과학회지
Korean Journal of Dermatology
;
: 103-108, 1987.
Article
in Korean
| WPRIM
| ID: wpr-84743
ABSTRACT
We report herein a case of polymorphic pemphigoid in a 65-year-old woman, who had one-year history of generlized polymorphic eruption with intensely pruritic excoriated vesicobiullous lesions and residual pigmentation. Face and oral mucosa were spared. The skin biopsy specimen showed a subepidermal blister containing many eosinophils. Linear deposition of 1gG and C3 along the basement membrane was noticed on direct irnmunofluorescerice. Polyclonal garnmopathy with a tendency of beta-gamma bridging and increased IgG, IgA and kappachain, was frund on serum protein electrophoresis and immunoelectrophoresis. Skin lesions were well coritrolled by a combined therapy of prednisolone(20 mg/d), dapsone(100 mg/d) and cyclophosphamide(100 mg/d) for 4 months. Direct immunofluorescence performed 11 rnonths after the cnmpletion of the therapy was negative.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Basement Membrane
/
Biopsy
/
Immunoglobulin A
/
Immunoglobulin G
/
Pigmentation
/
Immunoelectrophoresis
/
Blister
/
Pemphigoid, Bullous
/
Fluorescent Antibody Technique, Direct
Limits:
Aged
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1987
Type:
Article
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