Immunohistochemical Identification of Keratin in Cutaneous Tumors / 대한피부과학회지
Korean Journal of Dermatology
;
: 64-70, 1987.
Article
in Korean
| WPRIM
| ID: wpr-84749
ABSTRACT
Sixty cutaneous tumors of different types were investigated by means of immunoperoxidase technique(avidin-biotm-peroxidase complex method) with the use of antikeratin antibody. The results were as follows 1. Squamous cell carcinomas, keratoacanthomas, and Bowen's disease exhibited strong reactivity with antikeratin antibody. 2. In squamous cell carcinomas and keratoacanthomas, the most heaviest staining patterns were detected in areas of keratinization and horn pearl formation. 3. Basal cell carcinomas and seborrheic keratosis were moderately stained, whereas Paget'a disease and metastatic carcinoma(oat cell carcinoma) did not contain keratin. 4. In some cases of basal cell carcinomas, the tumor cells were partially positive. 5. Malignant melanomas, nevi, malignant.lymphomas, neural tumors, hemangiomas, and dermatofibromas were uniformly negative.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bowen's Disease
/
Carcinoma, Basal Cell
/
Carcinoma, Squamous Cell
/
Keratosis, Seborrheic
/
Histiocytoma, Benign Fibrous
/
Hemangioma
/
Horns
/
Keratoacanthoma
/
Melanoma
/
Nevus
Type of study:
Diagnostic study
Limits:
Animals
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1987
Type:
Article
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