Metrology and visual analysis of English literature regarding osteoporosis in the past 5 years: Based on the web of science / 中国组织工程研究

ABSTRACT

BACKGROUND: Osteoporosis has always been a hotspot in medical research. Visual analysis of English literature regarding osteoporosis can intuitively understand the research status, hotspots and frontiers in this field, and help researchers to hold on the research topic and direction. OBJECTIVE: To perform bibliometric, co-presence, co-citation, and visual analyses of English literature regarding osteoporosis, and to explore the relevant research status, research hotspots and dynamic frontiers in this field in the past 5 years. METHODS: The CiteSpace software was used for co-presence analysis of the authors, institutions, countries, and keywords and for co-citation analysis of cited authors, references, and journals in the 2015-2019 related literature included in the Science Citation Index Expanded (SCI-E) of Web of Science (WOS). RESULTS AND CONCLUSION: A total of 2 980 articles were included. High-yielding countries include China, the United States, Japan, South Korea, and the United Kingdom. The main research institutions are Pittsburgh University, Harvard University, McMaster University, Oxford University, and other world-renowned universities. Shanghai Jiao Tong University wins a place in the orthopedics research. As high-yielding authors, Hong-Wen Deng focuses on genetic and osteoporosis mechanisms; Hiroyuki Kato, Yukio Nakamura, and Takako Suzuki jointly focus on the development of anti-osteoporosis drugs such as denosumab and ibandronate; Jonathan D Adachi focuses on vitamin D and osteoporosis and bone metabolism research; William D Leslie focuses on dual-energy bone mineral density assessment of osteoporosis; JA Kanis focuses on the appropriate population and timing for anti-osteoporosis. Osteoporosis International and Journal of Bone and Mineral Research published the most of research regarding osteoarthritis. New England Journal of Medicine, LanceT, JAMA-J and other top publications are also very concerned about osteoporosis research. The research discipline involves clinical and basic disciplines, with a focus on basic subjects. Advances in the development of anti-osteoporosis drugs are an important entry point for basic medical research. Lack of osteoporosis, zoledronic acid, glucocorticoid-induced osteoporosis, fat mass, oophorectomy, osteoporosis, mineral density, ovarian cancer, anti-osteoporosis, and bone metabolism is the frontier of osteoporosis research. In 2015-2016, animal research and senile osteoporosis were hotspots. In 2016-2017, the design of randomized trials, adult bone metabolism, and physical activity interventions were emerging areas of osteoporosis research. In 2017-2019, glucocorticoid-induced osteoporosis, mesenchymal stem cells and activation of cellular pathways were emerging areas of osteoporosis research. To conclude, CiteSpace can be used to bibliometrically analyze the English literature of osteoporosis and intuitively reveal the overall development trend of osteoporosis research in the past 5 years. Therefore, it can provide references for osteoporosis scholars in the reference content and development direction of the topic, and the results have certain significance.