Osteosarcopenic obesity syndrome: Diagnosis, treatment and related influencing factors / 中国组织工程研究

ABSTRACT

BACKGROUND: Studies have shown that osteoporosis, sarcopenia and obesity are important factors affecting metabolic diseases such as fracture, hypertension and dyslipidemia. OBJECTIVE: To describe the prevalence and influencing factors of osteosarcopenic obesity and its effects on racture and dyslipidemia, and to explore the role of diet and exercise in preventing osteosarcopenic obesity, so as to provide theoretical basis for the prevention and treatment of osteosarcopenic obesity METHODS: The related articles Included In PubMed and WANFANG database published from 1990 to 2018 were searched using the following keywords Osteosarcopenlc obesity, sarcopenlc obesity, osteoporosis, sarcopenla, obesity, fracture, dysllpldemla, osteosarcopenlc obesity syndrome. The language was limited to “English” or “Chinese.” A total of 71 articles were Included for analysis and discussion. RESULTS AND CONCLUSION: (1) The age, sex, nationality or race differences in prevalence of osteosarcopenlc obesity have been found. The diagnostic criteria of osteosarcopenlc obesity, not international standard, have been established in the United States, Europe, Asia and others continents or countries; (3) Osteosarcopenlc obesity is affected not only by living and eating habits, but also by genes, cytokines and metabolic hormones. (4) Osteosarcopenic obesity exerts greater impact on fracture and dyslipidemia compared with osteoporosis, sarcopenia and obesity alone.