Biomechanical analysis of the lumbar spine and pelvis in adolescent idiopathic scoliosis with lumbar major curve / 中国组织工程研究

ABSTRACT

BACKGROUND: Adolescent idiopathic scoliosis causes changes in the structure and stress of the spine. The lumbar spine bears the greatest load in the spine, and the pelvis also plays the role of transmitting gravity. Therefore, the biomechanical analysis of the lumbar spine and pelvis in adolescent idiopathic scoliosis with lumbar major curve is particularly important. OBJECTIVE: To establish the three-dimensional digital model of lumbar spine-pelvis in adolescent idiopathic scoliosis and undergo finite element analysis. METHODS: The CT microscopic data of the lumbar spine-pelvis in a 13-year-old idiopathic scoliosis volunteer were used to reconstruct the three-dimensional digital model using mimics 15.0 software. The preliminary geometric model was established by Pro/E 5.0 software and imported into Hypermesh 13.0 for mesh generation. The model was finally subjected to finite element analysis by Abaqus 6.14 software. The displacement, stress changes of the model under six load conditions, and the stress changes of each vertebra and intervertebral disc were analyzed. The study was approved by the ethical committee of the hospital, and the patient family member signed the informed consents. RESULTS AND CONCLUSION: (1) A three-dimensional finite element model of the lumbar spine-pelvis in adolescent idiopathic scoliosis was established. (2) Under the six kinds of loading conditions, the displacement of the upper part of the Li was the largest in the left and right flexion, and the displacement of the lower end of the tibia was the largest in the flexion. (3) The right margin of the intervertebral disc had highest stress under right flexion. Under anterior flexion position, the lumbar intervertebral disc was subjected to the highest stress on the anterior margin and the stress on the left margin was the least stressed. The posterior margin had the highest stress under posterior extension. The edge was subjected to the least stress; when the lateral flexion and the rotational position, the right edge was subjected to the most stress, and the leading edge was subjected to the least stress. (4) L5 had the largest stress in all six movements, and the stress was concentrated on the upper and lower articular processes and pedicles, especially on the right side. (5) In summary, for adolescent idiopathic scoliosis, different loads may cause different stresses and displacement values of the vertebral body or intervertebral disc under different positions. These results are of great significance for the treatment and prevention of scoliosis.