Comparative study of ultrasound imaging of thyroid follicular carcinoma and adenoma / 肿瘤

ABSTRACT

Objective: Toexplore the value of ultra sound features in differentiating follicular thyroid carcinoma and thyroid adenoma. Methods: The ultrasound and clinical data of thyroid follicular carcinoma and adenoma were retrospectively analyzed. Each parameter was analyzed by Student’s t-test and monofactor analysis. The parameters with statistical significance were further analyzed by multivariate analysis. Results: There were statistical differences between follicular carcinoma and adenoma in borders, morphology, "tubercle-in-nodule", and "trabecular formation". In 24.1% of follicular cancers, the boundary of nodule was unclear; while most of the adenomas showed clear boundaries. In 50.6% of follicular cancers, the nodule morphology was irregular; while 83.0% of adenomas showed regular morphology. In 19.5% of follicular cancers, "tubercle-in-nodule" feature was showed; while only 5.7% of adenomas had "tubercle-in-nodule" feature. In 49.4% of follicular cancers, "trabecular formation" was found; while the proportion of adenomas with "trabecular formation" was 20.8%. Multivariate analysis showed that "trabecular formation" was statistically significant in the distinction between follicular carcinoma and adenoma. Conclusion: Trabecular formation as an ultrasound feature is helpful for the ultrasound diagnosis of follicular thyroid carcinoma.