Relationship between micro-calcification and prognostic factors in breast cancer patients / 肿瘤
Tumor
;
(12): 1202-1208, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-848465
ABSTRACT
Objective:
To investigate the correlation between the prognosis of breast cancer patients and mammographic calcification.Methods:
A total of 1 035 breast cancer patients with complete clin ical information were in cluded in this study. According to mammographic calcification before operation, the patients were divided into calcification group and non-calcification group, and then the expressions of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2) were compared between two groups. The influence of calcification on the positive expression rates of ER, PR and HER-2 and the relationship between calcification and tumor size, axillary lymph node status, histological grade, molecular classification and prognosis were analyzed.Results:
The rate of calcification in the patients with axillary node metastasis was significantly higher than that in the patients without lymphatic metastasis [53.6% (199/371) vs 47.1% (312/663)] (P 0.05). In survival analysis, there was no obvious difference between the calcification group and non-calcification group.Conclusion:
The breast cancer with micro-calcification shown on mammographic X-ray images was associated with the expression of HER-2, molecular typing and axillary lymph node status. The calcification is likely to have no effect on the survival of patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Tumor
Year:
2017
Type:
Article
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