Clinical observation on change of immunological function after chemotherapy in combination with ubenimex for malignant tumors / 肿瘤
Tumor
;
(12): 382-384, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-848962
ABSTRACT
Objective:
To explore the effect of chemotherapy in combination with ubenimex on immunological function of patients with malignant tumors.Methods:
The changes of counts of T-lymphocyte subsets and NK (natural killer) cells in peripheral blood of patients with malignant tumors after chemotherapy alone (n = 150) or in combination with ubenimex (n = 150) were examined by FCM (flow metry).Results:
The proportions of CD3+ and CD4+ T-lymphocyte subsets, NK cells (CD3-/CD16+ CD56 +) and the ratio of CD4+/CD8+ in peripheral blood of patients with malignant tumors after chemotherapy in combination with ubenimex were significantly higher than those of patients receiving chemotherapy alone (P < 0.05). The proportion of CD8+ T-lymphocytes was obviously lower in patients receiving chemotherapy in combination with ubenimex than that in patients receiving chemotherapy alone (P < 0.05).Conclusion:
Use of ubenimex may improve the immunological function of patients with malignant tumors after chemotherapy. Copyright © 2013 by TUMOR.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Tumor
Year:
2013
Type:
Article
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