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Clinical effect of breast-conserving surgery in early triple negative breast cancer / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army ; (12): 986-989, 2020.
Article in Chinese | WPRIM | ID: wpr-849648
ABSTRACT
Objective To investigate the effect of breast conserving surgery in early triple negative breast cancer (TNBC). Methods Data of 56 early (stage and Ⅱ) TNBC patients in the Eighth Medical Center of PLA General Hospital from January 2010 to January 2015 were analyzed retrospectively, and they were divided into breast-conserving surgery group (n=27) and modified radical surgery group (n=29) who chose the modified radical surgery due to their own willingness and economic factors. Patients in both groups received adjuvant chemoradiotherapy and were followed up for 5 years. Postoperative local recurrence rate, distal metastasis rate, 5-year survival rate, operative time, amount of bleeding, hospital stays, postoperative complications, Symptom Check List 90 (SCL90) were compared between the two groups. Results There were no significant differences in local recurrence rate, distant metastasis rate, operative time and survival rate between the breast-conserving surgery group and the modified radical surgery group (P>0.05). The postoperative complications, amount of bleeding, hospital stays in the breast-conserving surgery group were significantly lower than those in the modified radical surgery group (P<0.05). The SCL90 total score, total symptom index, positive items, and average of positive items of the patients who survived 5 years after the operation were also significantly lower than those of the modified radical surgery group (P<0.05). Conclusion Breast-conserving surgery for early TNBC patients is safe and effective. There was no significant difference in operation time between breast-conserving surgery and modified radical surgery, but breast-conserving surgery can shorten the postoperative recovery time, reduce surgical complications, and improve the postoperative quality of life.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Medical Journal of Chinese People's Liberation Army Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Medical Journal of Chinese People's Liberation Army Year: 2020 Type: Article