Correlation between the incidence of type 2 diabetes mellitus to Chinese visceral adiposity index in a community population of Chongqing City / 解放军医学杂志

ABSTRACT

Objective To investigate the correlation between the Chinese visceral adiposity index (CVAI) and the morbidity risk of type 2 diabetes mellitus (T2DM). Methods A total of 6426 subjects (3568 males, 2858 females) from a community of Chongqing City who participated in a medical examination in 2013 were recruited. After exclusion of faulty data or missing information, the final samples for analysis included 5039 subjects (2834 males, 2205 females). Subjects were firstly divided into male group and female group, and then, according to CVAI index quartiles, the both groups were respectively divided into 1st (Q1), 2nd (Q2), 3rd (Q3) and 4th (Q4) quantile group. Anthropometric data (including blood glucose, lipid levels, uric acid) were compared among each group. The risk of T2DM in subjects with different CVAI index was analyzed with logistic regression analysis. Results After adjusting possible confounding factors affecting diabetes, such as age, systolic pressure, diastolic pressure, levels of total cholesterol, triglyceride, low-density lipoprotein and uric acid, compared with the risks of T2DM in 1st (Q1) CVAI quartiles, that in 2nd (Q2), 3rd (Q3) and 4th (Q4) CVAI quartiles for males were 1.146 (OR=1.146, 95%CI 0.764-1.718), 2.033 (OR=2.033, 95%CI 1.378-3.000) and 3.247 (OR=3.247, 95%CI 2.175-4.849), and that in 2nd (Q2), 3rd (Q3) and 4th (Q4) CVAI quartiles for females were 1.583 (OR=1.583, 95%CI 0.634-3.954), 3.108 (OR=3.108, 95%CI 1.222-7.905) and 3.814 (OR=3.814, 95%CI 1.350-10.733). Conclusion Higher CVAI is the independent risk factor for the T2DM in Chinese adults.