Research progress on pediatric epilepsy genes and precision medicine / 解放军医学杂志

ABSTRACT

Ion channel genes have been a hot topic in research of genetic pathogenesis of epilepsy and antiepileptic drugs development. With the rapid development of epilepsy genetics, many non-ion channel genes have been found to be involved in the pathogenesis of epilepsy recent years, providing new targets for the development of anti-epileptic drugs beyond ion channels. The present paper aims to summarize the current ionic and non-ion channel genes that can be used to guide the precise treatment of epilepsy and their application in the precise treatment of epilepsy in children, so to provide reference for identifying the epilepsyassociated gene phenotype and formulating a precise treatment plan.