Encephalopathy associated with thyroid in adults / 解放军医学杂志

ABSTRACT

The thyroid is closely related to neurological diseases. Abnormal thyroid function may cause a series of metabolic-related central nervous system symptoms. Hyperthyroidism encephalopathy and hypothyroidism encephalopathy associated with thyroid dysfunction are rare in adults. Clinicians pay less attention to hyperthyroidism or hypothyroidism encephalopathy, which mainly present as mental and cognitive disorders, epileptic seizures, motor disorders and other nervous system symptoms as the first manifestation. These diseases are easily to be misdiagnosed. Hashimoto encephalopathy (HE) is a kind thyroid antibody-elevated and hormone-sensitive encephalopathy, has various clinical manifestations without specific auxiliary examination, and diagnosis can only be made by excluding other diseases. Whether "HE" is an independent disease remains controversial, as it is not clear whether thyroid auto-antibodies are specific to "HE" or the pathogenesis. Therefore, the present paper mainly focuses on the adult encephalopathy associated with abnormal thyroid function and thyroid antibody-associated encephalopathy.