Influence of interventional treatment of ventricular septal defect on QT dispersion, corrected QT dispersion and the left ventricular voltage / 解放军医学杂志

ABSTRACT

Objective To investigate the influence of interventional treatment of ventricular septal defect (VSD) on QT dispersion (QTd), corrected QT dispersion (QTcd) and the left ventricular voltage. Methods Fifty patients with VSD, admitted from May 2010 to October 2011 for interventional occlusion therapy, were included in the present study. The electrocardiograms and echocardiography of the patients were analyzed before and 1 day and 6 months after interventional treatment, including QTd, QTcd, RV5, SV1, RaVL, SV3, left ventricular ejection fraction (EF) and fractional shortening (FS). The changes in QTd, QTcd and the left ventricular voltage (RV5+SV1, RaVL+SV3) were observed after interventional occlusion therapy. Results Compared with preoperative electrocardiogram, the QTd and QTcd were obviously shortened (P<0.05), and the left ventricular voltage (RV5+SV1, RaVL+SV3) declined significantly after interventional occlusion therapy (P<0.05). Conclusions The QTd and QTcd are shortened and left ventricular voltage lowered significantly after interventional occlusion treatment in VSD patients. Transcatheter interventional occlusion therapy can obviously improve electrical remodeling.