Hemostatic effect of a medical polysaccharide hemostatic healing sponge on hemostasis of bleeding from femoral artery in pigs / 解放军医学杂志

ABSTRACT

Objective To study the effect of polysaccharide hemostatic healing sponge in controlling bleeding from femoral artery in miniature swines. Methods Thirty two miniature pigs were used to reproduce femoral artery hemorrhage model and then divided equally into four groups, and bleeding from femoral artery was treated by Medical Polysaccharide Hemostatic Healing Sponge (MP), carboxymethyl cellulose (CMC), gelatin sponge (GS) or medical gauze (MG), respectively. Hemostasis time, blood loss and vital signs of these pigs were observed and recorded. Results There were no group differences in mean arterial pressure. Hemostasis time was earlier and blood loss was less in MP, CMC and GS groups than in MG group, and the hemostatic effect was superior in CMC group to MP and GS groups and similar between the MP and GS groups. Conclusion MP or CMC dressing could effectively stop femoral artery bleeding, and its hemostatic effect is similar to or slightly better than GS in miniature pigs.