Sesquiterpenes and steroids from Subergorgia suberosa / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 5683-5689, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-850659
ABSTRACT
Objective:
To investigate the chemical constitutes of Subergorgia suberosa from South China Sea.Methods:
We carried out the chemical separation of EtOH extract of S. suberosa based on the chromatographic techniques such as medium pressure preparative chromatography, silica, sephadex LH-20, ODS column chromatography, and preparative thin layer chromatography (PTLC). The NMR and MS spectroscopic techniques, together with comparison with literature data, were used for structural elucidation of compounds.Results:
Fourteen compounds including sesquiterpenes and steroids were isolated from S. suberosa. These compounds were identified as subergorgic acid methyl ester (1), 2β-hydroxy subergorgic acid methyl ester (2), subergorgic acid (3), suberosenol A (4), suberosenol B (5), suberosenone (6), suberosanone (7), 3β-hydroxy-5β-pregnan-20-one (8), 3β-hydroxy-5α-pregnan-20-one (9), 3α-hydroxy-5β-pregnan-20-one (10), pregnan-4-ene-3,20-dione (11), 3β-hydroxy-pregnan-5-ene-20-one (12), cholesterol (13), and 5α,8α-epidioxyergosta-6,22-dien-3β-ol (14), respectively.Conclusion:
Compounds 5 and 10 are isolated from the family Subergorgiidae for the first time. Compound 14 is isolated from S. suberosa for the first time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2019
Type:
Article
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