Hydrosoluble chemical constituents in Sanguisorba officinalis (II) / 中草药

ABSTRACT

Objective: To study the chemical constituents in extract of Sanguisorba officinalis. Methods: Compounds were isolated from 10% ethanol extracts by Macroporous resin (D101, HP-20), dialysis bag, reversed phase silica gel (RP-8, RP-18), Toyopearl HW-40 column chromatography and their structures were elucidated by NMR and MS data. Results: Twenty-five compounds were isolated and their structures were elucidated as 4-(4’-hydroxyphenyl)-2-butanone-4’-O-β-D-glucopyranoside (1), phenethanol-β- vicianoside (2), junipetrioloside A (3), citroside A (4), corchoionoside C (5), adenosine (6), tryptophan (7), tachinoside (8), d-mandelic acid-β-D-glucopyranoside (9), (+) (7S,8S)-guaiacylglycerol 8-O-β-D-glucopyranoside (10), biophenol (11), 3,5-dihydroxyphenethyl alcohol 3-O-β-glucopyranoside (12), syringin (13), (2E,5E)-3,7-dimethyl-2,5-octadiene-1,7-diol (14), (±)-3-hydroxy-3,7-dimethyloct- 6-enoic acid (15), (2Z)-2,6-dimethyl-2,7-octadiene-1,6-diol (16), phlorizin (17), (+)-cyclo-olivil 6-O-β-D-glucopyranoside (18), 5’-methoxy-8’-hydroxyl-(+)-isolariciresinol-4’-O-β-D-gluco-pyranoside (19), phenethyl 6-O-α-L-arabinofuranosyl-β-D-glucoside (20), gaultherin (21), benzyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (22), (2E)-7-hydroxy-3,7-dimethyl-2-octenyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (23), 3,3’,4’-tri-O-methylellagic acid (24), and methyl-4-(β-D-glucopyranosyloxy)- 3-hydroxy-5-methoxybenzoate (25). Conclusion: Compounds 1-22 were isolated from this plant for the first time.