Chemical constituents from Rabdosia phyllopoda / 中草药

ABSTRACT

Objective: To investigate the chemical constituents of Rabdosia phyllopoda. Methods: The chemical constituents were isolated and purified by chromatography with silica gel, Sephadex LH-20 and by semi-preparative HPLC, and their structures were identified by analysis of spectroscopic evidences and physicochemical properties. Results: A total of 14 constituents were isolated from R. phyllopoda and elucidated as (Z)-1,1’-biindenyliden (1), β,β-carotene (2), germacrene B (3), 2α,3α,24-trihydrxyolean-12- en-28 oic acid (4), ferulic acid hexacosanyl ester (5), ergosterol peroxide (6), ursolic acid (7), α-amyrin acetate (8), obtusalin (9), betulinic acid (10), 2α,3α,19α-trihydroxy-12-en-28-urs acid (11), 2α,3α-dihydroxyl-12-ene-28 oic acid (12), 2α-hydroxyursolic acid (13), and lutein (14). Conclusion: The 14 compounds are isolated from this plant for first time, and compound 1, 3, 6, 9, 14 are isolated from the plants of R. phyllopoda for the first time.