Diterpenoid alkaloids in aerial parts of Aconitum transsectum / 中草药

ABSTRACT

Objective: To study the diterpenoid alkaloids in the aerial parts of Aconitum transsectum. Methods The compounds were isolated and purified by silica gel and Sephadex LH-20 chromatography from the aerial parts of A. transsectum, and the structures were identified by spectral analysis (1H-NMR, 13C-NMR, MS). Results: A total of 16 compounds were isolated from A. transsectum and characterized as longtoaconitine A (1), 14-acethyltalatisamine (2), 8-O-methylsachaconitine (3), talatisamine (4), vilmorrianine D (5), 14-acetylsachaconitine (6), forestine (7), chasmanine (8), crassicausine (9), homochasmanine (10), crassicautine (11), 8-deacetylyunaconitine (12), liljestrandisine (13), vilmorrianine B (14), yunaconitine (15), and isotalatizidine (16). Conclusion: Compounds 1-16 are isolated from aerial parts of A. transsectum for the first time, and compounds 1, 3, 9-11, 13-14, and 16 are isolated from A. transsectum for the first time.