A new meroterpenoid from Ganoderma resinaceum / 中草药

ABSTRACT

Objective: For the purpose of finding new agents, the chemical study on Ganoderma resinaceum was carried out. Methods: The chemical constituents from the dried fruiting bodies of G. resinaceum were isolated by column chromatographic methods of silica gel, MCI-Gel resin, and high performance liquid chromatography. The structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Results: Four compounds including one new meroterpenoid were isolated from this fungus. Their structures were identified as ganoresinains F (1), 3β,7β,15β-trihydroxy-11,23-dioxo-lanost-8,16-dien-26-oic acid (2), ganoderic acid XL2 (3) and 2,3-dihydro-4(1H)-quinolone (4). Conclusion: Compound 1 is a new compound and named as ganoresinains F (1).