The Effects of Remifentanil Pretreatment on Rocuronium Injection Pain and Cardiovascular Response during Anesthetic Induction / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 637-641, 2006.
Article
in Korean
| WPRIM
| ID: wpr-85127
ABSTRACT
BACKGROUND:
Remifentanil is an opioid agonist with rapid onset and ultra-short duration of action. Rocuronium bromide can elicit a high incidence of pain when intravenous injection. In this study, the quantitative effect of remifentanil pretreatment on the injection pain of rocuronium and cardiovascular response during anesthetic induction were evaluated.METHODS:
Eighty adult female patients undergoing gynecological procedures with general anesthesia were analyzed for this study. Patients were randomly allocated to one of four groups. Patients received 2 ml of normal saline (n = 20), 2 ml (40 mg) of 2% lidocaine (n = 20), 2 ml of remifentanil 0.5 microgram/kg (n = 20) or 2 ml of remifentanil 1 microgram/kg (n = 20) 60 seconds prior to administration of rocuronium 0.7 mg/kg. Pain was assessed after rocuronium injection. Systolic and diastolic arterial blood pressure and heart rates were measured before and during anesthetic induction.RESULTS:
Both remifentanil and lidocaine have the good effect in minimizing the rocuronium injection pain. But, only 1 microgram/kg of remifentanil blunts the hypertension after endotracheal intubation.CONCLUSIONS:
A bolus dose (1 microgram/kg) of remifentanil may be used for minimizing the rocuronium injection pain and blunting the hypertension after endotracheal intubation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Incidence
/
Arterial Pressure
/
Heart Rate
/
Hypertension
/
Injections, Intravenous
/
Intubation, Intratracheal
/
Anesthesia, General
/
Lidocaine
Type of study:
Incidence study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2006
Type:
Article
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