Chemical constituents from Pfaffia paniculata / 中草药

ABSTRACT

Objective: To study the chemical constituents from the roots of Pfaffia paniculata. Methods: The compounds were isolated and purified by means of chromatographic separation techniques and their structures were identified based on spectral features. Results: Fourteen known compounds, including 11 30-noroleanane triterpenoids and three ecdysterones, named pfaffianol A (1), 3-oxo-akebonoic acid (2), 16β-hydroxyl-3-oxo-akebonoic acid (3), pfaffiaglycoside A (4), pfameric acid (5), 2α,3β,20α-trihydroxy-30-norolean-12-en-28-oic acid (6), 2α,3β-dihydroxy-23-oxo-30-norolean-12,20(29)-dien-28-oic acid (7), 2α,3β-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid (8), 2α,3α-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid (9), quinatic acid (10), 3β-hydroxy-30-norhederagenin (11), diaulusterol B (12), 20,22-didehydrotaxisterone (13), and ecdysterone (14) were isolated from the roots of P. paniculata. Conclusion: Compounds 10-12 are obtained from P. paniculata for the first time. Compounds 6-9, and 13 are isolated from the genus of Pfaffia for the first time.