Effect of Feiliuping ointment combined with chemotherapy on cellular immune function and related inflammatory factors in patients with lung cancer / 中草药

ABSTRACT

Objective To study the effect of Feiliuping ointment combined with chemotherapy on the cellular immune function and related inflammatory factors in patients with lung cancer. Methods A total of 202 patients with non-small cell lung cancer (NSCLC) admitted to Henan Cancer Hospital from May 2014 to December 2016 were selected as subjects. They were randomly divided into the simple chemotherapy group (control group) and Feiliuping Ointment combined with chemotherapy group (observation group), and there were 101 cases in each group. The short-term curative effect, cellular immune function, and levels of inflammatory factors before and after treatment were observed and the adverse reactions were recorded. Results The effective rate and stability rate in the observation group were significantly higher than those in the control group (P < 0.05). Levels of CD3+, CD4+, CD4+/CD8+, and NK in the observation group after treatment were significantly higher than those in the control group (P < 0.05), while CD8+ was significantly lower than the control group (P < 0.05). Compared with the control group, the levels of serum IL-6, TNF-α, and hs-CPR were significantly lower in the observation group after treatment (P < 0.05). The incidence of adverse reactions in the observation group after treatment was significantly lower than that in the control group (P < 0.05). Conclusion Feiliuping Ointment combined with chemotherapy can effectively improve the clinical curative effect on lung cancer, regulate the immune mechanism, reduce the levels of inflammatory factors, improve the condition, and reduce the occurrence of adverse reactions in patients, thus deserving promoting.