Flavonoids isolated from capitula of Coreopsis tinctoria / 中草药

ABSTRACT

Objective To study the chemical constituents of the water extract of capitula of Coreopsis tinctoria. Methods The chemical constituents from water extract were isolated and prepared by silica gel column, reversed-phase ODS, and pre-HPLC, and their structures were identified according to the physical and chemical properties and spectral data. Results A total of 13 compounds were isolated and identified as 8,3’,4’-trihydroxyflavone-7-O-β-D-glucopyranoside (1), 6-Hydroxyluteolin-7-O-β-D-glucoside (2), kaempferol (3), quercetin-7-O-β-D-glucopyranoside (4), (2S)-3’,4’,5,8-tetrahydroxyflavanone-7-O-β-D-glucoside (5), (2S)- eriodictyol-5-O-β-D-glucoside (6), butin-7-O-β-D-glucopyranoside (7), plathymenin (8), (Z)-6-O-β-D-glucopyranosyl-6,3’,4’- trihydroxyaurone (9), 5,6,3’,4’-tetrahydroxyaurone (10), 6,3’,4’-trihydroxyaurone (11), okanin-5’-O-β-D-glucopyranoside (12), and 4’-O-β-D- glucopyranosyl-3,4,2’,4’,5’-pentahydroxychalcon (13). Conclusion Thirteen compounds are isolated from C. tinctoria for the first time.