Clinical Experiences Treating Edifenphos and Iprobenfos Intoxication Patients
Journal of the Korean Society of Emergency Medicine
;
: 149-153, 2012.
Article
in Korean
| WPRIM
| ID: wpr-85160
ABSTRACT
Organophosphate fungicides include edifenphos, iprobenfos and tolclofos-methyl. Edifenphos inhibits cell wall synthesis by reduction in chitin synthase activity and inhibits the action of acetylcholinesterase. Thus, exposure to this chemical results in excessive salivation, lacrimation, urination, defecation, gastrointestinal motility and emesis symptoms, just like other organophosphate insecticides. Although edifenphos is an organophosphate fungicide, it is the only agricultural chemical which inhibits the action of pralidoxime and atropine, an activity which in turn, inhibits treatment. Thus, we have to treat these cases as soon as possible with atropine and pralidoxime, using the same approach as used for exposure to other organophosphate insecticides. In this report we evaluate the results of treatment of 4 patients who were intoxicated by fungicides (3 cases with edifenphos and 1 case with iprobenfos).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organothiophosphorus Compounds
/
Pralidoxime Compounds
/
Acetylcholinesterase
/
Salivation
/
Atropine
/
Urination
/
Vomiting
/
Cell Wall
/
Chitin Synthase
/
Defecation
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Society of Emergency Medicine
Year:
2012
Type:
Article
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