Chemical constituents from aerial parts of Hypoestes phyllostachya / 中草药

ABSTRACT

Objective To study the chemical constituents from the aerial parts of Hypoestes phyllostachya. Methods The compounds were isolated and purified by silica gel column chromatography, MCI, and HPLC. Their structures were elucidated by spectroscopic analysis. Results Eighteen compounds were isolated from 95% ethanol aqueous extract of H. phyllostachya and the structures were identified as (3R,6R,7E)-3-hydroxy-megastigma-4,7-dien-9-one (1), (3S)-3-hydroxy-β-ionone (2), (3S,5R,6S,7E)-5,6-epoxy-3- hydroxy-megastigma-7-en-9-one (3), grasshopper ketone (4), vomifoliol (5), (+)-dehydrovomifoliol (6), loliolide (7), 2,6-dimethyl- 2E,7-octadien-1,6-diol (8), bifurcanol (9), (12S)-hydroxygeranylgeraniol (10), nectandrin B (11), N-trans-feruloyltyramine (12), syringylethanone (13), paeonol (14), vanillin (15), dehydrozingerone (16), 2-hydroxybenzyl alcohol (17), and (2E)-4-hydroxy-2- hexenoic acid (18). Conclusion All compounds are isolated from this plant for the first time.