Analysis on formula characteristics of health food with auxiliary protective function in chemical liver injury / 中草药

ABSTRACT

Through searching the information of chemical liver injury protection function of health food on the State Food and Drug Administration website and using Microsoft Excel 2016 software and Traditional Chinese Medicine Inheritance System, to analyze formula characteristics of health food and provide the basis for the formulation of health food with auxiliary protective function in chemical liver injury and the development of the product. A total of 325 kinds of health food were collected, of which 282 (86.8%) health food formulations contained Chinese materia medica (CMM) raw materials. The number of health food with one single health care function and two healthy functions was 192 and 133, respectively. In terms of dosage forms, there were 156 capsules, which account for about half of the total. Moreover, there were 21 kinds of CMM raw materials with more than 18 of the use frequency (f) and accumulated 768 times (73%). Nine new prescriptions were obtained by unsupervised entropy hierarchical clustering. The CMM is widely used in the health food which has the auxiliary protective function in the chemical liver injury. The choice of dosage forms is based on convenience of taking and carrying. Five commonly used functional ingredients are total flavonoids, crude polysaccharides, puerarin, total saponins, and taurine. The choice of CMM is basically consistent of the principle of traditional Chinese medicine treatment of chemical liver disease which are detoxification, strengthening the body resistance, promoting blood circulation, clearing away heat, dehumidification and so on. The most commonly used drugs are anti-alcoholismic drugs, tonic medicine, blood-activating and stasis-resolving drugs, heat-clearing drugs, and damp-draining diuretic. Nine new prescriptions found by software must be further evaluated in combination with the theory and practice of Chinese medicine and comprehensive analysis.