Chemical constituents from green alga Ulva pertusa / 中草药

ABSTRACT

Objective To investigate the chemical constituents from the ethanol extract of Ulva pertusa. Methods The compounds were isolated and purified by chromatography on silica gel, ODS, Diaion HP-20, Sephadex LH-20, and preparative HPLC methods. Their structures were elucidated on the basis of spectral data. Results Eighteen compounds were isolated and identified as isophitol (1), indole-3-carboxylic acid (2), 1-O-palmitoyl-3-O-(6'-sulfo-α-D-quinovopyranosyl) glycerol (3), (2S)-1-O-palmitoyl-3-O-[α-D- galactopyranosyl-(1→2)-β-D-galactopyranosyl] glycerol (4), 3-methylsulfoxypropionic acid (5), 3-chloropropionic acid (6), tyrosol (7), 4-hydroxybenzoic acid (8), 4-hydroxyphenylacetic acid (9), 6-vinyl hexanolide (10), loliolide (11), annuionone D (12), azelaic acid (13), succinic acid (14), 8-hydroxy-(6E)-octenoic acid (15), 3-ethoxypropionic acid (16), n-butyl β-D-fructopyranoside (17), and n-butyl pyroglutamate (18). Conclusion Compounds 1-16 are isolated from this alga for the first time, and compounds 5, 6, 10, 15, and 16 are obtained from natural products for the first time. Compounds 17 and 18 are artifacts of isolation from β-D-fructopyranoside and pyroglutamic acid.