Chemical constituents of petroleum ether soluble part from whole herbs of Mulgedium tataricum / 中草药

ABSTRACT

Objective: To isolate and identify the chemical constituents of petroleum ether soluble part of 60% aq. ethanol extracts from the whole herb of Mulgedium tataricum. Methods: Separation and purification were performed on silica gel column chromatography and recrystallization, PTLC, PHPLC, and related techniques. Their chemical structures were elucidated through spectroscopic analyses (NMR). Results: Nine compounds were isolated and identified as taraxasterol (1), pseudotaraxasterol (2), lupeol (3), olean-18-en-3β-ol (4), β-sitosterol (5), olean-18-en-3-one (6), 3β-hydroxy-taraxaster-20(30)-ene-28-oic acid (7), stigmasterol (8), and lupenone (9), respectively. Conclusion: Compounds 3, 4, 6, 7, and 9 are separated from this plant for the first time.