Chemical constituents of effective part in Celosia cristata for treatment of hemostatic / 中草药

ABSTRACT

Objective: To study the chemical constituents of effective fraction in Celosia cristata for hemostatic. Methods: The chemical constituents were isolated and purified by chromatography on silica gel, ODS, and preparative HPLC methods. Their structures were determined by physicochemical properties and spectral data. Results: Nine compounds have been found in the ethyl acetate fraction of 95% ethanol extraction from C. cristata which were obtained and identified as northalifoline (1), 1,2,3,4-tetrahydro-4-hydroxy-4-quinolin carboxylic acid (2), isorhamnetin-3-O-β-D-glucoside (3), 1-feruloyl-β-D-glucopyranoside (4), Feruloyl 6-O-β-D-glucopyranose ester [5 (α structure), 6 (β structure)], 2-methoxy-4-(2-propenyl) phenyl β-D-glucopyranoside (7), lupeol (8), and ferulic acid (9). Conclusion: All compounds are not only isolated from C. cristata for the first time but also from the plants of genus Celosia L. for the first time.