Study on Q-Marker of Leonurus japonicus and Penthorum chinense based on basic conditions of Q-Marker / 中草药

ABSTRACT

Quality control of Chinese materia medica (CMM), a key factor in restricting the development of modernization of CMM, has always been a hot issue to traditional Chinese medicine (TCM) circles, our society, and the public. At present, determination of chemical components is the main means for quality control of vast majority of CMM, but many components lack not only specificity, but also biological activities. This is bound to greatly reduce the value of quality standard of CMM, which makes it difficult to reflect the true quality of CMM. Quality marker (Q-Marker) of CMM is a new concept that brings forward higher requirement to quality control of CMM. Based on the basic conditions of Q-Marker, Leonurus japonicus and Penthorum chinense have been investigated systematically. This paper introduces theIR research processes from five aspects effective material basis, specificity of the isolated components, chemical structure and bioactivity, measurability, and fingerprint spectrum.