Chemical constituents of Nelumbinis Plumula / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the Seeds of Nelumbo nucifera. Methods: The chemical constituents were isolated by repeated silica gel chromatography, Sephadex LH-20 gel columns chromatography, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectroscopic analyses. Results: Thirteen compounds were identified to be p-methoxyphenylacetic acid (1), quercetin-3-O-α-L- arabinoside (2), apigenin-6-C-arabinoside-8-C-glucoside (3), naringenin (4), stigmast-4-en-3-one (5), quercetin-3-methyl ether (6), vitexin (7), cosmoslin (8), quercetin (9), apigennin (10), luteolin (11), kaempferol (12), and astragalin (13). Conclusion: Compounds 1-3, 5 and 6 are obtained from the plants of Nelumbo Adans for the first time, and compound 8 is obtained from Nelumbo plumula for the first time.