Chemical constituents from berries of Physalis pubescens / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the berries of Physalis pubescens. Methods: The constituents from the 80% ethanol extract of berries of P. pubescens were separated and purified by all several chromatographic technologies. The isolated compounds' structures were elucidated by physicochemical properties and spectral data analysis. Results: Nine compounds were isolated and purified. They were identified as 5-hydroxymethylfurfural (1), ethyl caffeate (2), β-sitosterol (3), trans-p-hydroxyl ethyl cinnamate (4), quercetin 3,5,7-trimethyl ether 3'-O-β-D-glucopyranoside (5), quercetin-3-O-(6'-O-trans-p-coumaroyl)-β-D-glucopyranoside (6), kaempferol-3-O-β-D-rutinoside (7), oleuropein (8), and 4,4'-diol-2'-methoxychalcone (9). Conclusion: Compounds 4-9 are obtained from the plants of genus Physalis L. for the first time, and compound 1 is isolated from P. pubescens for the first time.