Study on matrix proportion of hydrophilic SIS hot melt pressure sensitive adhesive suit modified by RLPO / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 748-751, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-853669
ABSTRACT
Objective:
To optimize the matrix proportion of SIS hot melt pressure sensitive adhesive suit for hydrophilic material releasing.Methods:
By orthogonal test method, taking adhesiveness and hydrophilic drug release rate as factors, and C5 petroleum resin hydrogenate, lanoline styrene-isoprene-styrene (SIS) triblock copolymer, ethyl acrylate-methyl methacrylate-trimethylamino (RLPO), liquid paraffin, dibutyl phthalate (DOP), polyethylene glycol (PEG) 400, and Antioxidant 1010 as materials, the matrix proportion was optimized.Results:
The optimized formulation was as follows SIS-C5 petroleum resin hydrogenate-SIS-RLPO-DOP-PEG 400-Antioxidant 1010 was 3466510.1. The adhesiveness was proper and shows more release rate for hydrophilic material.Conclusion:
The SIS hot melt pressure sensitive adhesive shows good property and is suitable to prepare transdermal patch.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2016
Type:
Article
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