Research progress on advanced pharmaceutical preparation and new dosage forms of dihydromyricelin / 中草药

ABSTRACT

As a major flavonoid in the leaves of Ampelopsis grossedentata, dihydromyricelin has attracted wide attention in recent years. The pharmacological effect of the dihydromyricelin is clear, but the limitation on the clinical application of this drug comes from its chemical properties and low bioavailability. Nowadays, researching on advanced pharmaceutical preparation and new dosage forms in order to improve its chemical properties has become hot spots. Based on the review of related literatures, we discussed the research progress on advanced pharmaceutical preparation and new dosage forms of dihydromyricelin, such as liposomes, microcapsules, microemulsions, solid dispersion, inclusion compound, floating gastroretentive drug, etc. The main purpose is to point out the shortages of existing research and provide a reference for further study.