Chemical constituents from pseudobulb of Cremastra appendiculata / 中草药

ABSTRACT

Objective: To study the chemical constituents from the pseudobulbs of Cremastra appendiculata. Methods: The compounds were isolated by repeated column chromatography with silica gel, Sephadex LH-20, and ODS-HPLC. The structures were elucidated by analysis of spectroscopic (1H-NMR and 13C-NMR) data. Results: Eleven compounds were isolated from the EtOAc extract in the pseudobulbs of C. appendiculata. Their structures were identified as 3,5,3'-trihydroxybibenzyl (1), 7-hydroxy-4- methoxy-phenanthrene-2-O-β-D-glucoside (2), lignan glycosides (3), ibotanolide A (4), 3,3'-dihydroxy-5-methoxy-2,4-di (p- hydroxybenzyl) bibenzy (5), 5,4'-bihydroxy-bibenzyl-3-O-β-D-glucoside (6), 3'-β-D-glucopyranosyloxy-4,5'-dihydroxy-3-methoxy- 1,2-diphenylethane (7), cirrhopetalanthin (8), 7-hydroxy-2-4-dimethoxy-phenanthrene (9), β-daucosterin (10), and p-hydroxy benzaldehyde (11). Conclusion: Compounds 3-7 are isolated from the pseudobulbs of C. appendiculata for the first time.