Chemical constituents from aerial parts of Glycyrrhiza uralensis / 中草药

ABSTRACT

Objective: To study the chemical constituents from the aerial parts of Glycyrrhiza uralensis. Methods: The compounds were isolated and purified by silica gel, Sephadex LH-20 column chromatography, and HPLC. The structures of the compounds were identified on the basis of chemical and spectral methods. Results: Twelve compounds were isolated from the ethanol extract of the the the aerial parts of G. uralensis and identified as (2S)-3'-(2-hydroxy-3-methylbut-3-enyl)-4',5,7-trihydroxy-dihydroflavanone (1), pinocembrin (2), sigmoidin B (3), licoflavanone (4), 6-prenylnaringenin (5), pinobanksin (6), galangin (7), genistein (8), pratensein (9), kaempferol-3-O-β-D-rutinoside (10), rutin (11), and α,α'-dihydro-3,5,3'-trihydroxy-4'-methoxy-5'-isopentenyl-stilbene (12). Conclusion: Compound 1 is a new compound named hydroxylicoflavanone, and compounds 3, 6, 7, and 9 are isolated from this plant for the first time.