Comparative study on different processes for Chinese materia medica Moutan Cortex and Cinnamomi Cortex formula granules containing volatile components / 中草药

ABSTRACT

Objective: To study the influence on the volatile components of Chinese materia medica (CMM) Moutan Cortex and Cinnamomi Cortex formula granules produced by different preparative processes. Methods: The different preparative processes were compared by determining the content of paeonol in Moutan Cortex formula granule and cinnamaldehyde in Cinnammi Cortex formula granule by HPLC. Results: The contents of paeonol in Moutan Cortex formula granule and cinnamaldehyde in Cinnamomi Cortex formula granule produced by conventional process were significantly lower than those by the other processes, which was carried out as follows extracting the volatile oil firstly, then drying the herb residue extract, adding the volatile oil by spaying directly or cyclodextrin inclusion finally. Conclusion: The best process of CMM Moutan Cortex and Cinnamomi Cortex formula granules containing volatile components was as follows extracting the volatile components firstly, then decocting the residues, and the volatile components was enclosed before adding in the granulation.