Chemical constituents from rhizomes of Valeriana jatamansi / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the rhizomes of Valeriana jatamansi. Methods: The ethanol percolation extraction was isolated and purified by ODS column, silica gel column, and Sephadex LH-20 chromatography. All compounds were identified on the basis of spectral analysis. Results: Thirteen compounds were isolated from the rhizomes of V. jatamansi and identified as prinsepoil (1), 8-hydroxypinoresinol (2), pinoresinol (3), 2,5-Methanocyclopenta-1,3-dioxin-7-ol (4), 3-(4-hydroxy-3-methoxyphenyl)-propenal (5), vibutinal (6), baldrinal (7), 11-ethoxyviburtinal (8), 5-hydroxymethyl furfural (9), pinoresinol-4'-O-β-D-glucoside (10), (7S,8R)-dehydroconiferyl alcohol-8,5'-dehydroconiferyl aldehyde-4-O-β-D-glucopyranoside (11), magnolol (12), and daucosterol (13). Conclusion: Compounds 11 and 12 are isolated from the plants in Valerianaceae for the first time, compounds 5 and 6 are isolated from the plants of Valeriana L. for the first time, and compounds 9 and 10 are isolated from this plant for the first time.